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Question

Which of the following gases makes the most stable combination with the haemoglobin of red blood cells?

A
CO2
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B
CO
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C
O2
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D
N2
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Solution

The correct option is B CO
  • The combination of oxygen with haemoglobin is called oxyhaemoglobin and this oxygenated blood is carried away from the lungs through the bloodstream to all the tissues of the body.
  • Carbon monoxide can also bind to haemoglobin but does so about 240 times more tightly than oxygen, forming a compound called carboxyhaemoglobin.
  • This means that if both carbon monoxide and oxygen are inhaled, carbon monoxide will preferentially bind to haemoglobin.
  • This reduces the amount of haemoglobin available to bind to oxygen, so the body and tissues become starved of oxygen.

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