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Question

Which of the following has the most acidic hydrogen?

A
3-Hexanone
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B
2,4-Hexanedione
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C
2,5-Hexanedione
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D
2,3-Hexanedione
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Solution

The correct option is B 2,4-Hexanedione
(a)

(b)

(c)

(d)

Here, (b) has most acidic hydrogen. Since in (b), C-3 is directly attached with two EWG (C=O) groups which make hydrogens at C-3 most acidic.

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