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Question

Which of the following hormones can cross the cell membrane of the target cell?

A
Epinephrine
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B
Follicle stimulating hormone
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C
Progesterone
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D
Prolactin
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Solution

The correct option is C Progesterone
Hormones bind to certain proteins called hormone receptors which are present on the cell membrane of the target cells or inside the target cells.

Lipid soluble hormones, which include steroid hormones and iodothyronines, can cross the cell membrane’s lipid bilayer and enter the target cell. They interact with intracellular receptors. Since progesterone is a steroid hormone, it can cross the cell.

Water soluble hormones, which include those that are amino-acid derivatives, peptides, polypeptides and proteins, interact with membrane-bound receptors. This interaction produces second messengers, which regulate cellular metabolism.

Epinephrine is an amino acid derivative hormone, and follicle stimulating hormone and prolactin are protein hormones. Therefore, these hormones cannot cross the cell membrane.

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