The correct option is A Estrogen
The mechanism shown in the diagram is the mechanism of lipid soluble hormones. Lipid soluble hormones, which include steroid hormones and iodothyronines, can cross the cell membrane and enter the cell. They interact with intracellular receptors. Estrogen is a steroid hormone.
Insulin and luteinizing hormone (protein hormones), and epinephrine (amino-acid derivative) are water soluble hormones. Water soluble hormones interact with membrane-bound receptors, since they cannot enter the cell.