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Question

Which of the following hormones uses calcium pathway for its action?


A

ACTH

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B

FSH

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C

LH

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D

CCK

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Solution

The correct option is D

CCK


CCK uses the calcium pathway for action. Hormones which can not enter cells (water-soluble) directly induce production of secondary messengers inside the cell for producing the desired effect. Two such pathways exist, one is the cAMP pathway and other is calcium or phosphatidylinositol pathway. Hormones ACTH, FSH, LH, PTH, glucagon, and calcitonin, all utilise the cAMP pathway, while CCK, TRH, GnRH, and gastrin utilise the phosphatidylinositol/calcium pathway.


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