Which of the following immunoglobulins is found as pentamer?
A
IgG
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B
IgM
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C
IgA
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D
IgE
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Solution
The correct option is B IgM Immunoglobulin M or IgM is a basic antibody that is produced by B cells. IgM is the largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen, It forms polymers and forms a pentamer.
IgM forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, mostly as a pentamer. IgM has a molecular mass of approximately 970 kDa. Because each monomer has two antigen binding sites, a pentameric IgM has 10 binding sites.