Which of the following inactivates the enzyme by changing its shape?

Competitive inhibitor

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Allosteric inhibitor

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Coenzyme

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All of the above

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Solution

The correct option is B Allosteric inhibitor
Allosteric means in a different steric conformation or occurrence of more than one shapes. Allosteric modulators bind to a site different from the active site and bring changes in the shape or conformation of the enzyme molecule. The change in shape can activate the enzyme or inhibit the activity of enzyme. An allosteric inhibitor will bind to allosteric site and bring in the conformational changes to reduce the enzyme activity.

Suggest Corrections

Column I	Column II
(A) Active site	(p) inactivates an enzyme by changing the enzymes's shape
(B) Alosteric inhibitor	(q) inactivates an enzyme by denaturing it
(C) Competitive inhibitor	(r) inactivates an enzyme by occupying its active site
(D) Substrate	(s) holds the substrate during the reaction
(E) Irreversible inhibitor	(t) molecules acted upon by an enzyme