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Question

Which of the following increases during allergies?

A
Plasma cells
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B
Lymphocytes
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C
Mast cells
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D
None of the above
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Solution

The correct option is C Mast cells
Mast cells play an important role during allergic inflammation. They contain many granules rich in histamine and heparin. Heparin acts as an anticoagulant and it is used to dissolve a blood clot. It is coated by IgE and it releases histamine when an allergen binds to the IgE which creates the allergic response. Histamine is a vasodilator that allows the flow of more blood and WBCs to the site where inflammatory response occurs.
So, the correct answer is option C.

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