Which of the following is a 5- carbon compound of Krebs cycle?

Citric acid

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Fumaric acid

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Oxalosuccinic acid

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α

-ketoglutaric acid

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Solution

The correct option is D $α$ -ketoglutaric acid
The first decarboxylation reaction in Krebs cycle is catalyzed by isocitrate dehydrogenase in which one six carbon atom compound isocitrate is decarboxylated to yield five carbon atom containing alpha ketoglutaric acid.

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α

α

C O_{2}

\begin{matrix} I . C i t r i c a c i d & \to & α - k e t o g l u t a r i c a c i d I I . S u c c i n i c a c i d & \to & M a l i c a c i d I I I . M a l i c a c i d & \to & O x a l o a c e t i c a c i d I V . α - k e t o g l u t a r i c a c i d & \to & S u c c i n y l C o - A \end{matrix}

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