Which of the following is a pentameric immunoglobulin and is produced first in a primary response to an antigen?
A
IgG
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B
IgM
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C
IgA
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D
IgE
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Solution
The correct option is A IgM IgM is the first immunoglobulin class produced in a primary response to an antigen. It is also the first immunoglobulin to be synthesised by a neonate. The pentameric nature of IgM confers higher valency on the molecule, and it can bind antigens like virus particles and RBC better since there are many antigen binding sites which can work simultaneously.