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Question

Which of the following is a wrong statement regarding mutations?

A
UV and gamma rays are mutagens
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B
Change in single base pair of DNA does not cause mutation
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C
Deletion and insertion of base pairs cause frame shift mutation
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D
Cancer cells commonly show chromosomal aberration
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Solution

The correct option is B Change in single base pair of DNA does not cause mutation
Mutation can be defined as a sudden change or alteration introduced into our DNA sequence. It can arise due to a variety of factors. Several chemicals or radiations cause mutation. Common high energy radiation sources include UV and gamma rays.
Mutation can be of several types. The type of mutation in which changes in a single base pair of DNA occur is known as point mutation. In other words, mutation involving a change in only a single nucleotide or nitrogen base of the cistron or gene is known as point mutation.
Insertion or deletion of base pairs alter the codons and hence, cause frameshift mutation.
Cancer commonly occurs due to mutations, one of the reason behind it is chromosomal aberration.

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