Question

Which of the following is an application of biosensor?

• A. Glucose monitoring in diabetes patients
• B. Protein engineering in biosensors
• C. Drug discovery and evaluation of biological activity of new compounds
• D. All of the above

Answer 1

The correct option is D All of the above

Biosensors are devices comprising a biological element and a physio-chemical detector that are used to detect analytes. These instruments have a wide range of applications.

Glucose monitoring: Diabetic patients have a relative or absolute lack of insulin, which is essential to the metabolism of a number of carbon sources. This deficiency causes various metabolic abnormalities, including higher than normal blood glucose levels. For such patients, insulin must be supplied externally. This has usually been achieved by subcutaneous injection.

Protein engineering: A protein-based electrochemical biosensor was developed for detection of tau protein aimed towards electrochemically sensing misfolding proteins. The electrochemical assay monitors tau–tau binding and misfolding during the early stage of tau oligomerization.

Drug discovery: Biofilm biosensors are an approach of whole-cell living biosensors for the development of bioreporters useful in environments monitoring and drug discovery. Green Fluorescent Protein biosensors is useful in antifungal drug discovery employing a transformed strain of Aureobasidium pullulans.

So, the correct answer is option D.