Question

Which of the following is/are true regarding mechanism of enzyme catalysis?

• A. It proceeds through lock and key model.
• B. Cavities present on the surface of the enzymes act as active centres for reactant molecules
• C. An activated complex formation takes place which then decomposes to form a product
• D. All of the above.

Answer 1

The correct option is D All of the above.

Mechanism of Enzyme Catalysis:
There are a number of cavities present on the surface of enzymes.
They are usually the active centers on the surface of enzyme particles.They possess active groups such as $-N{H}_2,-COOH,-SH,-OHetc.$
These cavities are of characteristic shape and fit into these cavities just like a key fits into a lock. On account of the presence of active groups, an activated complex is formed which then decomposes to yield the products.
As a results, the enzyme-catalysed reactions may be considered to proceed in two steps.
Steps Involves in Enzyme Catalyst Reaction
1. Binding of enzyme to substrate to form an activated complex
$E+S\to E{S}^{\ne }$
2.Decomposition of the activated complex to form product
$E{S}^{\ne }\to E+P$
Where, ​
$E$ : Enzyme​
$S$ : Substrate
$E{S}^{\ne }$: Activated complex
$P$: Product