Which of the following is biological uncoupler of oxidative phosphorylation?

2, 4-dichlorophenoxyacetic acid

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Keratin

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Thermogenin

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2,4-trinitrophenol

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Solution

The correct option is D Thermogenin
Thermogenin is also known as the uncoupling protein found in mitochondria as a transmembrane protein. It is responsible for decreasing the proton gradient generated by oxidative phosphorylation. This is done by returning the protons to the mitochondrial matrix by increasing the permeability of the inner mitochondrial membrane.
So, the correct answer is 'Thermogenin'

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