Question

Which of the following is correct for a double stranded DNA, according to the Chargaff's rule?

• A. A+T/G+C = Constant for all species
• B. A+U = G+C
• C. Percentage of Pyrimidines and Purines are not equal
• D. A+G = T+C

Answer 1

The correct option is D A+G = T+C

According to Chargaff’s rule in a double-stranded DNA:
1. Percentage base pair equality: %A = %T and %G = %C.
2. The percentage of pruines is equal to the percentage of pyrimidines A+G = T+C.
3. The A+T/G+C ratio is specific for a species.
4. The ratio of A +G/T+C equals to 1.

So of all the options given, A+G = T+C is correct.