Question

Which of the following is correct match?

• A. Thalassemia - XO- Flatnose, simian crease
• B. Down's syndrome - $42$AA $+$ XY-Webbing of neck
• C. Turner's syndrome - $44$AA$+$ XXX-Anaemia, jaundice
• D. Klinefelter's syndrome - $44$AA$+$ XXY- Tall, thin eunuchoid

Answer 1

The correct option is D Klinefelter's syndrome - $44$AA$+$ XXY- Tall, thin eunuchoid

Klinefelter syndrome is a sex chromosome disorder in boys and men that results from the presence of an extra X chromosome in cells. People typically have 46 chromosomes in each cell, two of which are the sex chromosomes. Females have two X chromosomes (46, XX), and males have one X and one Y chromosome (46, XY). But in rare cases, a male is born with an extra X chromosome (XXY). This is Klinefelter syndrome. Adults with Klinefelter syndrome are usually taller than nonaffected adult males, reaching a mean final height of about 185 cm (73 in). XXY males also have disproportionately long arms and legs. Males born with Klinefelter's syndrome may have low testosterone and reduced muscle mass, facial hair and body hair. Most males with this condition produce little or no sperm.

So, the correct answer is 'Klinefelter's syndrome - 44AA+ XXY- Tall, thin eunuchoid'.