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Question

Which of the following is correct regarding AIDS causative agent HIV?
I. HIV is an enveloped virus containing one molecule of single-stranded RNA and one molecule of reverse transcriptase.
II. HIV is an enveloped virus that contains two identical molecules of single-stranded RNA and two molecules of reverse transcriptase.
III. HIV is unenveloped retrovirus.
IV. HIV does not escape but attacks the acquired immune response. (NEET-II 2016)

A
I, II and III
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B
I, III and IV
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C
II and IV
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D
I and III
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Solution

The correct option is C II and IV
HIV is a spherical virus with a diameter of about 90-120 nm. Its genome consists of a single-stranded RNA filament segmented into two identical filaments and associated with reverse transcriptase enzymes. The envelope consists of a lipid bilayer derived from host cell membrane and projecting knob-like glycoprotein spikes. It contains two protein coats.

HIV is a retrovirus that attacks helper T cells. Without an adequate supply of helper cells, the immune system cannot signal B cells to produce antibodies to kill infected cells, thus the body becomes susceptible to infections. This immune deficiency is described by the name Acquired Immunodeficiency Syndrome or AIDS.

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