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Question

Which of the following is likely to accumulate in dangerous proportions in the blood of a person whose kidney is not working properly?

A
Sodium chloride
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B
Ammonia
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C
Lysine
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D
Urea
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Solution

The correct option is D Urea
Nitrogenous wastes are the most important metabolic wastes excreted by the kidneys.

As the liver breaks down amino acids it also releases ammonia. The liver then quickly combines that ammonia with carbon dioxide, creating urea which is the primary nitrogenous end product of metabolism in humans.

The liver turns the ammonia into urea because it is much less toxic. Therefore, urea is likely to accumulate in dangerous proportion in the blood of a person whose kidney is not working properly.

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