Question

Which of the following is not a reason for infertility in females?

• A. Implantation of embryo in the fallopian tube due to its permanent blockage
• B. Inability of the fimbriae to transport the oocyte
• C. Y-chromosome deletions
• D. Chronic inflammation of the endometrium

Answer 1

The correct option is C Y-chromosome deletions

Infertility is a condition in which a couple is unable to bear a progeny naturally due to defects in either the male partner or female partner or even both of them. Discussing about the possible reasons of female sterility could include reasons like
I. Anovulation- absence of ovulation (release of oocyte from the mature follicle)
II. Decreased level of gonadotropins LH and FSH which prevents maturation of follicles and ovulation.
III. Defective growth of uterus and vagina
IV. Chronic endometritis- inflammation of the endometrium of the uterus, making it unsuitable for implantation.
V. The complete inability of the fimbriae of the fallopian tube to pick the secondary oocyte from the ovary
VI. Female reproductive tract is hostile to sperms
VII. Ectopic pregnancies- implantation of the embryo occurs repeatedly at any site in the female reproductive tract, other than the uterus. However, treatment may help to achieve viable pregancies.

Complete blockage of fallopian tube stops transport of gametes.

These could be the various possible reasons for prolonged infertility in females.

Y-chromosome deletions cause infertility as the Y-chromosome contains specific regions that are responsible for the production of one or more proteins needed for normal sperm cell development. As a result, either few sperm develop or sperm do not develop at all, leading to Y-chromosome linked infertility.