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Question

Which of the following is not correct ?


A

Glomerular hydrostatic pressure - blood against the wall of glomerular capillaries - 60 mmHg

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B

Capsular hydrostatic pressure - exerted by the filtrate in the Bowman's space - 20 mmHg.

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C

Oncotic pressure - exerted by protein present in the capillary - 30 mmHg

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D

Net filtration pressure = GHP + (CHP - OP) = 50 mm of Hg.

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Solution

The correct option is D

Net filtration pressure = GHP + (CHP - OP) = 50 mm of Hg.


Hydrostatic pressure is the force exerted by the blood against the wall of the capillary. This pressure pushes solutes and water out of the vessel and into bowman's space. The hydrostatic pressure inside the glomerular capillaries called the GHP or the glomerular hydrostatic pressure is relatively high because of the pressure at which systemic blood is pumped and tends to be about 60 mmHg. Similarly, the hydrostatic pressure in the Bowman's capsule called the capsular hydrostatic pressure or CHP is the pressure exerted by the filtrate in the Bowman's space. This tends to be about 20 mmHg. Oncotic pressure is the pressure exerted by proteins, which tends to pull water into the vessel, like sponges. The oncotic pressure or OP in the capillaries depends on the concentration of protein present in the capillary. This tends to be about 30 mmHg. Net filtration pressure (NFP) or the glomerular filtration pressure GFP tends to be

GHP - (CHP+OP) = 60 - (20+30) = 10 mm of Hg.


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