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Question
Which of the following is the connecting link between glycolysis and Krebs cycle?
Which of the following is the connecting link between glycolysis and Krebs cycle?
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Solution
The correct option is A Acetyl CoA
The end product of glycolysis is pyruvic acid or pyruvate. The site of glycolysis is cytoplasm. The site of Krebs cycle is mitochondria. Pyruvate enters mitochondria through a specific transport protein. It undergoes oxidative decarboxylation to produce CO2 and NADH. The pyruvic acid combines with coenzyme A to form acetyl CoA. The reaction occurs in the presence of an enzyme complex pyruvate dehydrogenase. This step is called the link reaction or transition reaction or gateway step as it links glycolysis with Krebs cycle. The acetyl CoA combines with oxaloacetic acid to form a six carbon molecule called citric acid in the Krebs cycle.
The end product of glycolysis is pyruvic acid or pyruvate. The site of glycolysis is cytoplasm. The site of Krebs cycle is mitochondria. Pyruvate enters mitochondria through a specific transport protein. It undergoes oxidative decarboxylation to produce CO2 and NADH. The pyruvic acid combines with coenzyme A to form acetyl CoA. The reaction occurs in the presence of an enzyme complex pyruvate dehydrogenase. This step is called the link reaction or transition reaction or gateway step as it links glycolysis with Krebs cycle. The acetyl CoA combines with oxaloacetic acid to form a six carbon molecule called citric acid in the Krebs cycle.
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