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Question

Which of the following is true regarding the active site of an enzyme?

A
The enzyme catalyzes a reaction through its active site
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B
All the above
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C
The substrate binds to the active site
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D
The active site is formed by the foldings and crevices in the tertiary structure
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Solution

The correct option is B All the above
In the tertiary structure of the protein, the polypeptide chain folds upon itself and forms many crevices and pockets. Active site is one such crevice or pocket in which the substrate fits and binds to an enzyme. With the binding of substrate, the active site activates the enzyme and the enzyme catalyzes the reaction. Hence, all the given statements are true.

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