Question

Which of the following is used as the mitotic spindle poison?

• A. $C{a}^{+}$
• B. $M{g}^{+}$
• C. Tubulin
• D. Colchicine

Answer 1

The correct option is D Colchicine

A spindle poison is a poison that interrupts the cell division by affecting the spindles. There are several spindle poisons such as mebendazole, colchicine, vinca alkaloids, taxol. Colchicine is an alkaloid. It inhibits the microtuble polymerization which is essential to mitosis.

Thus, the correct answer is option D.