Which of the following is used by Human immunodeficiency virus (HIV) to integrate its own DNA into a host cell's genome?
A
DNA polymerase
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B
Helicase
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C
Primase
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D
Ligase
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E
Reverse transcriptase
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Solution
The correct option is E Reverse transcriptase HIV (Human Immunodeficiency Virus) has a viral envelope, matrix proteins and core. The viral core consists of two single strands of RNA. RNA genome containing retroviruses have reverse transcriptase enzyme that synthesizes a DNA copy (cDNA) of viral RNA. This cDNA can be introduced in the hosts' genome and allowed to replicate to form viral proteins.
Thus, the correct answer is option 'Reverse transcriptase'.