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Question

Which of the following lack mitochondria?
(i) Erythrocytes
(ii) Neutrophils
(iii) Platelets
(iv) Monocytes

A
(i) Only
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B
(i), (ii), (iv)
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C
(i), (ii), (iii)
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D
(i), (iii)
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Solution

The correct option is A (i) Only
Mammalian red blood cells (erythrocytes) contain neither nucleus nor mitochondria.Mitochondria participate in aerobic (i.e., in the presence of oxygen) cellular respiration. Red blood cells transport oxygen; by lacking mitochondria, RBCs use none of the oxygen they transport.

Neutrophils possess mitochondria, which do not synthesize ATP, have limited specific enzymatic activity.

Platelets possess mitochondria. Monocytes possess mitochondria. Mitochondria play a crucial role in the immune system particularly in regulating the responses of monocytes and macrophages to tissue injury, pathogens, and inflammation.

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