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Question

Which of the following layer of epidermis in man provides the main protection of body against water loss and the entry of disease causing organisms?

A
Stratum spinosum
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B
Stratum corneum
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C
Stratum lucidium
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D
Stratum granulosum
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Solution

The correct option is B Stratum corneum
Stratum corneum is the most superficial layer of skin and has keratinized cells. Keratin is a waterproof substance and protects the body from water loss and water gain. Presence of sebaceous glands that serve to weaken or kill the bacteria on skin allow the layer to serve as mechanical barrier against microbe invasion. Stratum spinosum, stratum lucidium, and stratum granulosum are internal to stratum corneum. So, the correct answer is option B.
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