Which of the following metabolites enter the TCA cycle during glucose oxidation?

Oxaloacetic acid

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Pyruvic acid

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Acetyl CoA

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Malic acid

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Solution

The correct option is B Acetyl CoA
Glycolysis is a cytosolic process and will break a molecule of glucose into two molecules of pyruvic acid. Each molecule of pyruvic acid is oxidatively decarboxylated to acetyl coA by the action of an enzyme complex pyruvate dehydrogenase. The acetyl coA then enters the Krebs (TCA) cycle. Thus, acetyl CoA forms the link between glycolysis and Krebs (TCA) cycle.
Thus, the correct answer is option C.

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