Which of the following method was used for the first test tube baby program?
In Vitro Fertilization or IVF was the first test tube baby programme. This method is successful in those couples having trouble with fertilization of the egg by the sperm, due to problems in transport, irregular ovulation, etc. First, the woman is given medication to induce ovulation of several eggs in a cycle. These eggs are harvested and fertilized with sperm taken from the father. Fertilisation takes place in a culture dish designed to replicate the conditions in a woman’s uterus. Once the embryo has sufficiently matured usually after 3 to 5 days, it is inserted into the uterus of the donor mother for further development. This process of embryo transfer into the mother’s uterus is known as intrauterine transfer.
GIFT is transfer of gametes inside the fallopian tube.
ZIFT is transfer of embryo inside the fallopian tube.
And ICSI is injection of sperm into the ovum to ensure fertilisation in a petridish.