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Question

Which of the following options describes the individual with deteriorated first line of defence?

A
Patient receiving immunosuppressive drugs
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B
Degeneration of thymus in children
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C
Loss of memory immune response after failure to follow up vaccination
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D
Patient receiving treatment after severe burn
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Solution

The correct option is D Patient receiving treatment after severe burn

Persons who survive a severe burn have damaged skin because the epidermal layer of skin gets destroyed completely. Skin, being the first line of defence, is impermeable to the infecting agent due to the presence of the stratum corneum layer (epidermis), which gets destroyed after severe burn.

Patients receive immunosuppressive drugs in case of organ transplantation so that the transplant can be accepted by the recipient without any life-threatening immune reaction.

The thymus begins to degenerate after puberty.

Vaccination is a mode of generating immune response inside the human body either by stimulating antibody production or by directly injecting readymade antibodies. Vaccination is the third line of defence.


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