Which of the following pair is characterized by swollen lips, thick pigmented skin of hands and legs and irritability?

Thiamine- Beri-Beri

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Protein- Kwashiorkor

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Nicotinamide- Pellagra

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Iodine- Goitre

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Solution

The correct option is D Nicotinamide- Pellagra
Niacin or nicotinamide is a water soluble vitamin. It is essential for normal metabolism as it is a precursor of coenzyme nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). Its deficiency causes pellagra and canine disease (black tongue). Pellagra is characterized by swollen lips, thick pigmented skin of hands and legs and irritability.

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