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Question

Which of the following pairs of hormones are not antagonistic to each other?

A
Relaxin- Inhibin
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B
Parathormone- Calcitonin
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C
Insulin- Glucagon
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D
Aldosterone- Atrial natriuretic factor
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Solution

The correct option is C Relaxin- Inhibin
A. Relaxin is a protein hormone secreted by placenta. It dilates the cervix and aids in childbirth.
Inhibin is secreted from ovaries and inhibits the release of FSH (Follicle stimulating hormone).
B. Parathormone is secreted from the parathyroid hormone and increases blood calcium level by increasing the reabsorption of calcium from the bones.
Calcitonin is secreted from the C-cells of thyroid gland and acts on bone and kidneys to reduce blood calcium level.
C. Insulin is secreted from the β cells of islets of Langerhans of pancreas. Insulin acts on hepatocytes and adipocytes and increases the uptake of cellular glucose and its utilisation. Thus, it decreases blood glucose level.
Glucagon is secreted from alpha cells of islets of Langerhans of pancreas. It increases blood sugar level by stimulating glycogenolysis (i.e. break down of glucose) and gluconeogenesis (synthesis of glucose).
D. Aldosterone is a mineralocorticoid hormone secreted from the adrenal cortex. It maintains the electrolyte balance in the body by reducing the loss of sodium through urine and sweat.
Atrial natriuretic factor is secreted from heart and stimulates excretion of sodium in kidneys.
Hence, hormones in option A are not antagonistic to each other.
So, the correct answer is 'Relaxin- Inhibin'.

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