Question

Which of the following reaction does not involve Hoffmann bromamide degradation?

• A.
• B.
• C.
• D.

Answer 1

The correct option is D

(a) It involve Hoffmann bromamide degradation.

(b) Partial hydrolysis of nitrile under basic condition gives amide which undergoes Hoffmann bromamide degradation.

(c) Reaction of acyl chloride with excess of ammonia gives amide which undergoes Hoffmann bromamide degradation.
(d) Compound having methyl ketone moeity gives haloform reaction. Reduction of amide with LAH furnishes primary amine.