Which of the following reaction needs catalyses by decarboxylase enzyme?

Conversion of citric acid to cis-aconitic acid

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Fumaric acid to malic acid

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Oxalosuccinic acid to

α

-ketoglutaric acid

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Malic acid to oxaloacetic acid

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Solution

The correct option is C Oxalosuccinic acid to $α$ -ketoglutaric acid
Oxalosuccinate is decarboxylated to form $α$ -ketoglutarate through the enzyme decarboxylase. It is one of the steps involved in Krebs cycle. It releases one molecule of $C O_{2}$ .
Oxalosuccinate $D e c a r b o x y l a s e \to M g^{2 +} α$ -ketoglutarate $+ C O_{2}$

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C O_{2}

\begin{matrix} I . C i t r i c a c i d & \to & α - k e t o g l u t a r i c a c i d I I . S u c c i n i c a c i d & \to & M a l i c a c i d I I I . M a l i c a c i d & \to & O x a l o a c e t i c a c i d I V . α - k e t o g l u t a r i c a c i d & \to & S u c c i n y l C o - A \end{matrix}

α

N A D^{+}

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