Which of the following reactions can be used to prepare above given product ?
A
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B
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C
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D
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Solution
The correct option is B Grignard reagent is a strong nucleophile. It undergoes nucleophilic addition reaction when it reacts with aldehyde, ester and ketone.
Grignard reagent react with formaldehyde to form 1∘ alcohol.
Grignard reagent react with aldehyde except formaldehyde to form 2∘ alcohol.
Grignard reagent react with ketone to form 3∘ alcohol.
The given compound is tertiary (3∘) alcohol with one methyl and 2 ethyl group so to prepare it we need ketone and grignard reagent which is in option (a) and (b) but to get the 2 ethyl group and one methyl group reaction (b) is suitable. Hence correct option is (b).
The reaction is as follow: