The correct option is A 20 g of H2O (Molar mass=18.02 g/mol)
1 mole of a substances will have NA number of molecules, so the molecule with the least number of moles will have the least number of molecules.
Number of moles=given massmolar mass
For 20 g H2O,number of moles =2018=1.11 moles
For 77 g CH4,number of moles =7716=4.81 moles
For 60 g CaH2,number of moles =6842=1.62 moles
For 100 g N2O,number of moles =10044=2.27 moles
As water has the least number of moles, hence it will have the least number of molecules.