Question

Which of the following sets of syndromes shows $47$ chromosomes in their genetic make up?

• A. Turner's syndrome, Edward's syndrome, Klinefelter's syndrome
• B. Klinefelter's syndrome, Turner's syndrome, Patau's syndrome
• C. Down's syndrome, Patau's syndrome, Edward's syndrome
• D. All the above

Answer 1

Answer: (C)

Down's syndrome, Patau's syndrome, Edward's syndrome

• Down's syndrome is a genetic disorder caused by the presence of all or part of the third copy of chromosome 21. Hence it shows 47 chromosomes in the genetic makeup.
• Patau's syndrome is a condition in which a person has an extra chromosome 13. Hence it shows 47 chromosomes in the genetic makeup.
• Edward's syndrome is a condition that causes severe developmental delays due to an extra chromosome 18. Hence it shows 47 chromosomes in the genetic makeup.

So, the correct answer is 'Down's syndrome, Patau's syndrome, Edward's syndrome'.