Which of the following stage is affected by colchicine?

Metaphase

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Prophase

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Interphase

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Anaphase

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Solution

The correct option is A Metaphase
Organisation of spindle apparatus is an important event of metaphase stage. Colchicine is obtained from Colchicum autumnale. This drug does not allow spindle formation in a cell during cell division. Tubulin is mostly used to form the spindle fibres which is inhibited by the colchicine. It is also known as a mitotic poison.
So, the correct answer is option A.

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