Question

Which of the following statement describes that genes encode the amino acid sequence of proteins?

• A. Proteins are macromolecules
• B. RNA directs amino acid synthesis
• C. The amino acid sequence of polypeptides is changed by gene mutation
• D. DNA serves as a template for RNA
• E. mRNA is found in the ribosome

Answer 1

Answer: (C)

The amino acid sequence of polypeptides is changed by gene mutation

Gene mutations cause changes in the sequence of the nucleotides that code for the amino acid sequence. Mutations either deletes, inserts, translocates or replaces any nucleotide with another nucleotide that causes the sequence to change.

Example: In sickle cell anaemia, the glutamic acid is replaced by valine due to change in codon sequence. According to genetics, GAG codon changes to GTG due to point mutation.

So, the correct option is 'The amino acid sequence of polypeptides is changed by the gene mutation.'