Question

Which of the following statement is correct regarding the mechanism of action of ANF?

• A. It causes vasodilation.
• B. It is secreted in response to high blood pressure.
• C. It is secreted in response to high blood volume.
• D. All of the above.

Answer 1

The correct option is D All of the above.

ANF(Atrial natriuretic factor) is synthesized and secreted by cardiac muscle cells in the walls of the atria in the heart. When the blood pressure is increased due to high blood volume the heart needs to pump more blood it results in the stretch in the walls of atria which releases ANF in the circulatory blood. Then ANF acts on the blood vessels and causes vasodilation. ANF is secreted in response to high blood pressure and high blood volume and causes vasodilation which results in lowering of blood pressure hence maintains homeostasis.

So, the correct answer is 'All the above'.