Question

Which of the following statements about the conformation (secondary and tertiary structure) of proteins is FALSE?

• A. The presence of the amino acid pro-line has the effect of turning a corner in a protein.
• B. The four atoms of an amide linkage (CONH) lie in a plane as a result of resonance between the nitrogen and the carbonyl group.
• C. Electrostatic attraction occurs between basic and acidic side chains.
• D. The favored conformation of a protein is always that which has the greatest number of hydrogen bonds.

Answer 1

The correct option is D The favored conformation of a protein is always that which has the greatest number of hydrogen bonds.

Here statement in option D is False.

Confirmation of protein is determined by the sequence of amino acids but not on hydrogen bonds.

All other statements are correct.

Proline causes a turning effect due to steric hindrance.

$CONH$ lies in one plane for resonance

Electrostatic attraction occurs between acidic and basic side chains forms $1°$ and $2°$ structures.

Hence, Option D.