Question

Which of the following statements are correct?

(i) $C{a}^{+2}$ is necessary for blood coagulation.
(ii)Coagulation in blood vessel is prevented during normal condition by heparin.
(iii)Clotting of blood involves changes of fibrinogen to fibrin by thrombin.
(iv)Blood clotting involves cascading process involving a number of factors present always in the active form.

• A. (i), (iii) and (iv)
• B. (ii) and (iv)
• C. (i) and (iii)
• D. (iii) and (iv)

Answer 1

The correct option is C (i) and (iii)

Ca$+2$ is necessary for blood coagulation -

1. Conversion of prothrombin to thrombin, in presence of prothrombin activator and Ca${+2)$

2. Conversion of fibrinogen monomers in to fibrin fibres

III fibrinogen is thin soluable protein that is converted to insoluable protein fibres by thrombin

So, the correct answer is 'i and iii'