Question

Which of the following statements is correct with reference to enzymes?

• A. Apoenzyme = Holoenzyme + Co-enzyme
• B. Holoenzyme = Apoenzyme + Co-enzyme
• C. Co-enzyme = Apoenzyme + Holoenzyme
• D. Holoenzyme = Co-enzyme + Co-factor
  

Answer 1

The correct option is B Holoenzyme = Apoenzyme + Co-enzyme

Holoenzyme is the active form of the enzyme. It is made of two components called the apoenzyme and co-factor.

• The protein part of an enzyme is called apoenzyme.
• The non-protein part is called co-factor. Co-factor may be prosthetic group, co-enzyme and metal ion.

Association of the co-factor with the apoenzyme is necessary for the proper functionality of the enzyme.