Question

Which of the following statements is incorrect with respect to aneuploidy?

• A. It is caused due to failure of chromatid segregation
• B. It is caused due to failure of cytokinesis
• C. It results in lack or excess copies of a particular chromosome(s)
• D. Down’s syndrome is an example of aneuploidy

Answer 1

The correct option is B It is caused due to failure of cytokinesis

Aneuploidy is the condition characterized by the loss or gain of one or few chromosomes leading to an unbalanced chromosome complement.

It is caused due to the failure of the homologous chromosomes to separate during meiosis I or sister chromatids to separate during meiosis II.

One of the examples is Down’s syndrome in which the affected individual has three copies of the ${21}^{st}$ chromosome in all the diploid cells.

Failure of cytokinesis leads to the presence of multiple sets of chromosomes in a cell. This condition is called polyploidy.