Which of the following statements is not correct about oxidative decarboxylation?

It takes place in mitochondrial matrix

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Two molecules of NADH are produced by one molecule of pyruvate

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Pyruvate dehydrogenase is used as catalyst in this reaction

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Two molecules of NADH are produced by two molecules of pyruvate

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Solution

The correct option is B Two molecules of NADH are produced by one molecule of pyruvate
The pyruvate which is formed by glycolysis enters into mitochondrial matrix undergoes oxidative decarboxylation by a catalyst called pyruvate dehydrogenase. During this process, two molecules of NADH are produced from the metabolism of two molecules of pyruvic acid. This reaction can be shown by the following equation:
Mg2+

Pyruvic acid+CoA+NAD⁺ -------------------------------->Acetyl CoA+Co₂+NADH + H⁺

Pyruvate dehydrogenase

Hence, the correct answer is option B.

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