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Question

Which of the following statements is not correct regarding colchicine?

A
It prevents assembly of microtubules
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B
It inhibits chromosome replication
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C
It is an alkaloid
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D
It is called as mitotic poison
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Solution

The correct option is C It inhibits chromosome replication
Colchicine is an alkaloid widely used in plant breeding for doubling the chromosome number. The alkaloid does not allow the formation of spindle because it prevents assembly of microtubules. It is therefore called 'mitotic poison'. Colchicine holds the cells in metaphase. Colchicine does not inhibit chromosomes replication.
So, the correct answer is 'It inhibits chromosome replication'.

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