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Question

Which of the following types of antibodies is most unlikely to harm the sperms?

A
IgG
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B
IgM
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C
IgA
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D
IgD
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Solution

The correct option is D IgD
Antibodies that target the sperms in semen and kill them are called antisperm antibodies. It occurs when the immune system of our body mistakenly targets the sperms in the semen as a foreign antigen and damages or kills it. These antibodies can be formed in both males and females. In males, these can be formed when there is an infection in the prostate gland or injury to the testicles. In any of the conditions, when the sperms come in contact with blood, a series of immunological reactions are set off which give rise to antisperm antibodies.
In females, who are allergic to semen can produce these antibodies. The presence of these antibodies in the vagina can kill the sperms.
IgG, IgA, and IgM are identified to be antisperm antibodies. IgE and IgD are not antisperm antibodies.

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