Question

Which of the following undergoes change in mutation?

• A. Chromosome
• B. Structure of gene
• C. Sequence of gene
• D. Any of the above

Answer 1

The correct option is D Any of the above

Mutations are the changes in chemical structure of genes which are manifested in altered protein structure and function. It can alter the sequence of nucleotides in a gene by inversion, deletion, substitution or frameshift changes. DNA replication errors or chemical and physical mutagens disturb the structure of nucleotides and mutate the gene. Structural (inversion, deletion, duplication, translocation) and numerical (aneuploidy, polyploidy) changes in chromosomes are called as chromosomal aberrations which produce the same phenotypic effect as gene mutations. Thus, mutations can change sequence, structure of gene as well as structure of chromosomes.