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Question

Which of these is a product of the urea cycle?

A
Ammonia
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B
Citrulline
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C
Aspartate
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D
Fumarate
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Solution

The correct option is D Fumarate
The urea cycle is a cycle of biochemical reactions that produces urea from ammonia. This cycle occurs in ureotelic organisms.

Ammonia and carbon dioxide combine to enter the cycle. Ornithine along with another intermediate forms citrulline. Citrulline binds to aspartate; this requires ATP. This finally leads to formation of arginine, and in the process fumarate is released. Arginine is converted to ornithine, in which reaction water is used up and urea is produced. The ornithine regenerated in this step again takes part in the cycle.
In this cycle, urea and fumarate are the products.

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