(c) It can be the site of energy generation
The function of the ER is to serve as channels for the transport of materials (especially proteins) between various regions of the cytoplasm or between the cytoplasm and the nucleus. The ER also functions as a cytoplasmic framework providing a surface for some of the biochemical activities of the cell. In the liver cells of the group of animals called vertebrates, the SER helps in the manufacture of fat molecules, or lipids, important for cell function and also SER plays a crucial role in detoxifying many poisons and drugs. Mitochondria are the site of energy generation