wiz-icon
MyQuestionIcon
MyQuestionIcon
1
You visited us 1 times! Enjoying our articles? Unlock Full Access!
Question

Which of these statements is not true about IgM?

A
the first antibody to be produced by neonates
No worries! We‘ve got your back. Try BYJU‘S free classes today!
B
the first antibody produced in primary and secondary immune response
No worries! We‘ve got your back. Try BYJU‘S free classes today!
C
trimeric in nature having 6 antigen binding sites
Right on! Give the BNAT exam to get a 100% scholarship for BYJUS courses
D
present in blood because it cannot diffuse into tissues because of its higher molecular weight
No worries! We‘ve got your back. Try BYJU‘S free classes today!
Open in App
Solution

The correct option is C trimeric in nature having 6 antigen binding sites
Immunoglobulin M (IgM) is one of several isotypes of antibodies that are produced by the vertebrates. IgM is the first antibody developed in foetal development. IgM antibodies react to quickly recognise and initiate an immune response by directly neutralising the pathogens or clearing the novel antigens.

IgM is the first antibody to be produced in both primary and secondary immune response. IgM antibodies are the largest antibodies with the biggest size, as it is pentameric (except monomeric on the B cell receptors) in nature having approximately 970 kDa of weight with 10 antigen binding sites and hence they cannot diffuse into tissues.

flag
Suggest Corrections
thumbs-up
0
Join BYJU'S Learning Program
similar_icon
Related Videos
thumbnail
lock
Immunity - In Depth
BIOLOGY
Watch in App
Join BYJU'S Learning Program
CrossIcon